Peptides Side Effects – Understand The Risks And How They Compare To Alternatives

Peptides Side Effects – Understand The Risks And How They Compare To Alternatives

Since their first introduction to the medical and performance supplements market, peptides have grown in popularity as well as effectiveness. Over the past 20 years many of these synthetic drugs have gone through extensive clinical trials and testing.

The result has been an increased understanding of how they work, and more importantly, what their side effects are. Here at AG Pharma we offer several of these peptides and in order to source the best products we have done extensive research into what these clinical trials have concluded.

All of the below side effects have been encountered with different types of peptides, but it is important to note, that they are not all associated to the same drugs.

We will also show you how peptides compare to traditional steroids so that you have a better understanding of how limited these side effects are relatively speaking.

Let’s start with some of the effects noted in clinical trials.

Potential Side Effects

The following is a list of different side effects that are the most commonly encountered. They are not all to be expected at the same time with just one product. However, if you’re planning to stack multiple products, then you could notice several of these.

Water Retention

This is by far the most common side effect that you have to keep in mind. At the levels encountered in clinical trials this is not a dangerous negative. But what can happen is that you might mistake the retained water in muscle tissue as bulking up.

As soon as the dosage is reduced this retention will disappear. Having shorter cycles and regular post cycle times with reduced or no peptide intake will help you get the full picture of your progress.

Reduced Testosterone

In rarer situations it can happen that natural testosterone levels in the body can decrease. This is definitely something that needs to be carefully monitored as the knock on effects can be substantial. Things to keep an eye out for are reduced hair growth, mood swings and even an increase BMI as less fat is burned.

While this doesn’t happen often or to a significant extent, this would be counterproductive to any physical goals set. The best thing to do in this case is to switch to a different product.


This is an increased and more pronounced development of the breast tissue in men. It can go pretty much unnoticed as your chest muscles bulk up more, but in the long run you may notice softer and fatty tissue developing.

This is generally the result of hormonal imbalances where oestrogen increases and testosterone decreases from normal levels.

The effect is fully reversible by stopping the intake and continuing training and possibly substituting the product for one that burns body fat.

Increased Cortisol

Cortisol is a hormone that is directly linked to the body’s sensitivity to stress. Whether that is physical stress from hard work or mental stress, the results can lead to a heightened feeling of anxiety and overall stress.

If you find yourself stressing over things that you never did before, then it’s best to avoid the chosen product. While clinical studies only showed very minimal increases, these could still trigger some effects if you’re naturally more prone to react to stress.

Blood Sugar

With most peptides designed to increase muscle mass and burn away fat, the body will at some stage struggle to provide the necessary energy. It is absolutely vital that you make sure you adjust your diet to your training plan and supplements in order to make sure your blood sugar levels don’t drop too low.

If you find yourself struggling to keep your energy levels up, especially during training, then a reduced dosage or increased food intake will be necessary.

Increased Appetite

Similar to the reduced blood sugar levels, it is going to be likely that your appetite increases. This is especially the case once you reduce your BMI and there is little to no body fat to use as a source of energy.

When you notice this increase in hunger, then it is vital to make sure that you plan your food intake. You will need an increased calorie intake, but it’s important that it’s well balanced and healthy.

Sex Drive

Proclatin is a hormone that directly impacts the amount of testosterone and oestrogen is released. Both of these hormones directly impact libido, and in extreme situations can cause impotence.

While studies did shoe that proclatin levels did increase dosage dependent, this was not to very high levels. Certainly nowhere near as high as is common with traditional steroids (more on this below).

Headaches And Dizziness

In some cases test subjects have reported some dizziness immediately after taking the peptides. This was significantly linked to the dosage amounts, so if you do find that such effects take place, then you should try lowering the dosage or else switching to a different product.

How Do Peptides Compare To Steroids?

Despite all these different types of side effects that have been documented through clinical trials, peptides are still an excellent option for many reasons. The overall impact of these effects is fully reversible and in the majority of cases they are very mild.

When you compare that to traditional hormonal steroids that often involve direct intake of testosterone, then side effects have been known to be very severe.

Everything from severe mood swings and aggression to enlarged prostate can have lasting effects. And because these steroids trigger processes in the entire body, there is little to no control over the effects they have.

Final Thoughts

Peptides are not as selective as SARMs, resulting in more side effects. However, this should not mean they are not a viable option for many different types of uses and clinical testing. With careful monitoring of intake and dosage it is possible to trigger very specific anabolic processes.

From fat burning to increased muscle tissue development, there is plenty of room for positive effects, without the serious impacts commonly associated to steroids.